What is the main reason enteric-coated tablets should remain intact?

Enteric-coated tablets are specifically designed to protect the active ingredients from being released in the acidic environment of the stomach. Instead, these tablets are intended to dissolve in the more alkaline environment of the intestines, where the active ingredients can be absorbed more effectively.

By remaining intact until reaching the intestines, enteric-coated tablets help prevent potential irritation that the medication might cause to the stomach lining. Many medications can be harsh on the stomach or may cause discomfort; therefore, the coating serves a protective function by allowing the drug to bypass the stomach. This targeted release is crucial not only for minimizing side effects but also for maximizing the medication's effectiveness by ensuring it is absorbed in the appropriate part of the digestive tract.

This is particularly important for patients with sensitive stomachs or conditions that might exacerbate irritation, making the enteric coating a vital feature of these medications.